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Scientists See Signs of Lasting Immunity to Covid-19, Even After Mild Infections

globalresearchsyndicate by globalresearchsyndicate
August 17, 2020
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Scientists See Signs of Lasting Immunity to Covid-19, Even After Mild Infections
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Notably, several of the new studies are finding these powerful responses in people who did not develop severe cases of Covid-19, Dr. Iyer added. Some researchers have worried that infections that take a smaller toll on the body are less memorable to the immune system’s studious cells, which may prefer to invest their resources in more serious assaults. In some cases, the body could even jettison the viruses so quickly that it fails to catalog them. “This paper suggests this is not true,” Dr. Iyer said. “You can still get durable immunity without suffering the consequences of infection.”

The Coronavirus Outbreak ›

Frequently Asked Questions

Updated August 12, 2020

  • Can I travel within the United States?

    • Many states have travel restrictions, and lots of them are taking active measures to enforce those restrictions, like issuing fines or asking visitors to quarantine for 14 days. Here’s an ever-updating list of statewide restrictions. In general, travel does increase your chance of getting and spreading the virus, as you are bound to encounter more people than if you remained at your house in your own “pod.” “Staying home is the best way to protect yourself and others from Covid-19,” the C.D.C. says. If you do travel, though, take precautions. If you can, drive. If you have to fly, be careful about picking your airline. But know that airlines are taking real steps to keep planes clean and limit your risk.
  • I have antibodies. Am I now immune?

    • As of right now, that seems likely, for at least several months. There have been frightening accounts of people suffering what seems to be a second bout of Covid-19. But experts say these patients may have a drawn-out course of infection, with the virus taking a slow toll weeks to months after initial exposure. People infected with the coronavirus typically produce immune molecules called antibodies, which are protective proteins made in response to an infection. These antibodies may last in the body only two to three months, which may seem worrisome, but that’s perfectly normal after an acute infection subsides, said Dr. Michael Mina, an immunologist at Harvard University. It may be possible to get the coronavirus again, but it’s highly unlikely that it would be possible in a short window of time from initial infection or make people sicker the second time.
  • I’m a small-business owner. Can I get relief?

    • The stimulus bills enacted in March offer help for the millions of American small businesses. Those eligible for aid are businesses and nonprofit organizations with fewer than 500 workers, including sole proprietorships, independent contractors and freelancers. Some larger companies in some industries are also eligible. The help being offered, which is being managed by the Small Business Administration, includes the Paycheck Protection Program and the Economic Injury Disaster Loan program. But lots of folks have not yet seen payouts. Even those who have received help are confused: The rules are draconian, and some are stuck sitting on money they don’t know how to use. Many small-business owners are getting less than they expected or not hearing anything at all.
  • What are my rights if I am worried about going back to work?

  • What is school going to look like in September?

    • It is unlikely that many schools will return to a normal schedule this fall, requiring the grind of online learning, makeshift child care and stunted workdays to continue. California’s two largest public school districts — Los Angeles and San Diego — said on July 13, that instruction will be remote-only in the fall, citing concerns that surging coronavirus infections in their areas pose too dire a risk for students and teachers. Together, the two districts enroll some 825,000 students. They are the largest in the country so far to abandon plans for even a partial physical return to classrooms when they reopen in August. For other districts, the solution won’t be an all-or-nothing approach. Many systems, including the nation’s largest, New York City, are devising hybrid plans that involve spending some days in classrooms and other days online. There’s no national policy on this yet, so check with your municipal school system regularly to see what is happening in your community.

What has been observed in people who fought off mild cases of Covid-19 might not hold true for hospitalized patients, whose bodies struggle to marshal a balanced immune response to the virus, or those who were infected but had no symptoms at all. Research groups around the world are continuing to study the entire range of responses. But “the vast majority of the cases are these mild infections,” said Jason Netland, an immunologist at the University of Washington and an author on the paper under review at Nature. “If those people are going to be protected, that’s still good.”

This new spate of studies could also further assuage fears about how and when the pandemic will end. On Friday, updated guidance released by the Centers for Disease Control and Prevention was misinterpreted by several news reports that suggested immunity against the coronavirus might last only a few months. Experts quickly responded, noting the dangers of propagating such statements and pointing to the wealth of evidence that people who previously had the virus are probably at least partly protected from reinfection for at least three months, if not much longer.

Considered with other recent reports, the new data reinforce the idea that, “Yes, you do develop immunity to this virus, and good immunity to this virus,” said Dr. Eun-Hyung Lee, an immunologist at Emory University who was not involved in the studies. “That’s the message we want to get out there.”

Some illnesses, like the flu, can plague populations repeatedly. But that is at least partly attributable to the high mutation rates of influenza viruses, which can quickly make the pathogens unrecognizable to the immune system. Coronaviruses, in contrast, tend to change their appearance less readily from year to year.

Still, much remains unknown. Although these studies hint at the potential for protectiveness, they do not demonstrate protection in action, said Cheong-Hee Chang, an immunologist at the University of Michigan who was not involved in the new studies. “It’s hard to predict what’s going to happen,” Dr. Chang said. “Humans are so heterogeneous. There are so many factors coming into play.”

Research in animals could help fill a few gaps. Small studies have shown that one bout of the coronavirus seems to protect rhesus macaques from contracting it again.

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