GLOBAL RESEARCH SYNDICATE
No Result
View All Result
  • Login
  • Latest News
  • Consumer Research
  • Survey Research
  • Marketing Research
  • Industry Research
  • Data Collection
  • More
    • Data Analysis
    • Market Insights
  • Latest News
  • Consumer Research
  • Survey Research
  • Marketing Research
  • Industry Research
  • Data Collection
  • More
    • Data Analysis
    • Market Insights
No Result
View All Result
globalresearchsyndicate
No Result
View All Result
Home Data Analysis

Unique homeobox codes delineate all the neuron classes of C. elegans

globalresearchsyndicate by globalresearchsyndicate
August 19, 2020
in Data Analysis
0
Unique homeobox codes delineate all the neuron classes of C. elegans
0
SHARES
5
VIEWS
Share on FacebookShare on Twitter

  • 1.

    Zeng, H. & Sanes, J. R. Neuronal cell-type classification: challenges, opportunities and the path forward. Nat. Rev. Neurosci. 18, 530–546 (2017).

    CAS 
    PubMed 

    Google Scholar
     

  • 2.

    Hench, J. et al. The homeobox genes of Caenorhabditis elegans and insights into their spatio-temporal expression dynamics during embryogenesis. PLoS ONE 10, e0126947 (2015).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 3.

    Sebe-Pedros, A. et al. Cnidarian cell type diversity and regulation revealed by whole-organism single-cell RNA-seq. Cell 173, 1520–1534 (2018).

    CAS 
    PubMed 

    Google Scholar
     

  • 4.

    Zeisel, A. et al. Molecular architecture of the mouse nervous system. Cell 174, 999–1014 (2018).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 5.

    Tasic, B. et al. Shared and distinct transcriptomic cell types across neocortical areas. Nature 563, 72–78 (2018).

    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 6.

    Hodge, R. D. et al. Conserved cell types with divergent features in human versus mouse cortex. Nature 573, 61–68 (2019).

    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 7.

    Gehring, W. J. Master Control Genes in Development and Evolution: The Homeobox Story (Yale Univ. Press, 1998).

  • 8.

    Way, J. C. & Chalfie, M. mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans. Cell 54, 5–16 (1988).

    CAS 
    PubMed 

    Google Scholar
     

  • 9.

    Finney, M., Ruvkun, G. & Horvitz, H. R. The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors. Cell 55, 757–769 (1988).

    CAS 
    PubMed 

    Google Scholar
     

  • 10.

    White, J. G., Southgate, E. & Thomson, J. N. Mutations in the Caenorhabditis elegans unc-4 gene alter the synaptic input to ventral cord motor neurons. Nature 355, 838–841 (1992).

    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • 11.

    Jin, Y., Hoskins, R. & Horvitz, H. R. Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein. Nature 372, 780–783 (1994).

    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • 12.

    Hobert, O. A map of terminal regulators of neuronal identity in Caenorhabditis elegans. Wiley Interdiscip. Rev. Dev. Biol. 5, 474–498 (2016).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 13.

    Tsuchida, T. et al. Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell 79, 957–970 (1994).

    CAS 
    PubMed 

    Google Scholar
     

  • 14.

    Lindtner, S. et al. Genomic resolution of DLX-orchestrated transcriptional circuits driving development of forebrain GABAergic neurons. Cell Rep. 28, 2048–2063 (2019).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 15.

    Stettler, O. & Moya, K. L. Distinct roles of homeoproteins in brain topographic mapping and in neural circuit formation. Semin. Cell Dev. Biol. 35, 165–172 (2014).

    CAS 
    PubMed 

    Google Scholar
     

  • 16.

    Tahayato, A. et al. Otd/Crx, a dual regulator for the specification of ommatidia subtypes in the Drosophila retina. Dev. Cell 5, 391–402 (2003).

    CAS 
    PubMed 

    Google Scholar
     

  • 17.

    Blochlinger, K., Bodmer, R., Jack, J., Jan, L. Y. & Jan, Y. N. Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila. Nature 333, 629–635 (1988).

    ADS 
    CAS 
    PubMed 

    Google Scholar
     

  • 18.

    Sugino, K. et al. Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain. eLife 8, e38619 (2019).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 19.

    Davis, F. P. et al. A genetic, genomic, and computational resource for exploring neural circuit function. eLife 9, e50901 (2020).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 20.

    Allen, A. M. et al. A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord. eLife 9, e54074 (2020).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 21.

    White, J. G., Southgate, E., Thomson, J. N. & Brenner, S. The structure of the nervous system of the nematode Caenorhabditis elegans. Phil. Trans. R. Soc. Lond. B 314, 1–340 (1986).

    ADS 
    CAS 

    Google Scholar
     

  • 22.

    Hobert, O., Glenwinkel, L. & White, J. Revisiting neuronal cell type classification in Caenorhabditis elegans. Curr. Biol. 26, R1197–R1203 (2016).

    CAS 
    PubMed 

    Google Scholar
     

  • 23.

    Bürglin, T. R. & Affolter, M. Homeodomain proteins: an update. Chromosoma 125, 497–521 (2016).

    PubMed 

    Google Scholar
     

  • 24.

    Bürglin, T. R., Finney, M., Coulson, A. & Ruvkun, G. Caenorhabditis elegans has scores of homoeobox-containing genes. Nature 341, 239–243 (1989).

    ADS 
    PubMed 

    Google Scholar
     

  • 25.

    Lambert, S. A. et al. The human transcription factors. Cell 172, 650–665 (2018).

    CAS 
    PubMed 

    Google Scholar
     

  • 26.

    Fuxman Bass, J. I. et al. A gene-centered C. elegans protein–DNA interaction network provides a framework for functional predictions. Mol. Syst. Biol. 12, 884 (2016).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 27.

    Murray, J. I. et al. Automated analysis of embryonic gene expression with cellular resolution in C. elegans. Nat. Methods 5, 703–709 (2008).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 28.

    Yemini, E. et al. NeuroPAL: a neuronal polychromatic atlas of landmarks for whole-brain imaging in C. elegans. Preprint at https://www.biorxiv.org/content/10.1101/676312v1 (2019).

  • 29.

    Hobert, O. Terminal selectors of neuronal identity. Curr. Top. Dev. Biol. 116, 455–475 (2016).

    CAS 
    PubMed 

    Google Scholar
     

  • 30.

    Merabet, S. & Mann, R. S. To be specific or not: the critical relationship between Hox and TALE proteins. Trends Genet. 32, 334–347 (2016).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 31.

    Packer, J. S. et al. A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution. Science 365, eaax1971 (2019).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 32.

    Cao, J. et al. Comprehensive single-cell transcriptional profiling of a multicellular organism. Science 357, 661–667 (2017).

    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 33.

    Kratsios, P. et al. An intersectional gene regulatory strategy defines subclass diversity of C. elegans motor neurons. eLife 6, e25751 (2017).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 34.

    Schneider, J. et al. UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit. Development 139, 2234–2245 (2012).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 35.

    Hobert, O. Development of left/right asymmetry in the Caenorhabditis elegans nervous system: from zygote to postmitotic neuron. Genesis 52, 528–543 (2014).

    PubMed 

    Google Scholar
     

  • 36.

    Serrano-Saiz, E. et al. Modular control of glutamatergic neuronal identity in C. elegans by distinct homeodomain proteins. Cell 155, 659–673 (2013).

    CAS 
    PubMed 

    Google Scholar
     

  • 37.

    Serrano-Saiz, E., Oren-Suissa, M., Bayer, E. A. & Hobert, O. Sexually dimorphic differentiation of a C. elegans hub neuron is cell autonomously controlled by a conserved transcription factor. Curr. Biol. 27, 199–209 (2017).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 38.

    Pereira, L. et al. A cellular and regulatory map of the cholinergic nervous system of C. elegans. eLife 4, e12432 (2015).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 39.

    Lloret-Fernández, C. et al. A transcription factor collective defines the HSN serotonergic neuron regulatory landscape. eLife 7, e32785 (2018).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 40.

    Doitsidou, M. et al. A combinatorial regulatory signature controls terminal differentiation of the dopaminergic nervous system in C. elegans. Genes Dev. 27, 1391–1405 (2013).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 41.

    Dobzhansky, T. Biology, molecular and organismic. Am. Zool. 4, 443–452 (1964).

    CAS 
    PubMed 

    Google Scholar
     

  • 42.

    Dickinson, D. J., Pani, A. M., Heppert, J. K., Higgins, C. D. & Goldstein, B. Streamlined genome engineering with a self-excising drug selection cassette. Genetics 200, 1035–1049 (2015).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 43.

    Dokshin, G. A., Ghanta, K. S., Piscopo, K. M. & Mello, C. C. Robust genome editing with short single-stranded and long, partially single-stranded DNA donors in Caenorhabditis elegans. Genetics 210, 781–787 (2018).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 44.

    Sarov, M. et al. A genome-scale resource for in vivo tag-based protein function exploration in C. elegans. Cell 150, 855–866 (2012).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 45.

    Feng, W. et al. A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life. eLife 9, e50065 (2020).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 46.

    Patel, T. & Hobert, O. Coordinated control of terminal differentiation and restriction of cellular plasticity. eLife 6, e24100 (2017).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 47.

    Leyva-Díaz, E. & Hobert, O. Transcription factor autoregulation is required for acquisition and maintenance of neuronal identity. Development 146, dev177378 (2019).

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 48.

    Schindelin, J. et al. Fiji: an open-source platform for biological-image analysis. Nat. Methods 9, 676–682 (2012).

    CAS 
    PubMed 

    Google Scholar
     

  • 49.

    Cassata, G. et al. The LIM homeobox gene ceh-14 confers thermosensory function to the AFD neurons in Caenorhabditis elegans. Neuron 25, 587–597 (2000).

    CAS 
    PubMed 

    Google Scholar
     

  • 50.

    Way, J. C. & Chalfie, M. The mec-3 gene of Caenorhabditis elegans requires its own product for maintained expression and is expressed in three neuronal cell types. Genes Dev. 3 (12A), 1823–1833 (1989).

    CAS 
    PubMed 

    Google Scholar
     

  • 51.

    Miller, D. M., III & Niemeyer, C. J. Expression of the unc-4 homeoprotein in Caenorhabditis elegans motor neurons specifies presynaptic input. Development 121, 2877–2886 (1995).

    CAS 
    PubMed 

    Google Scholar
     

  • 52.

    Kellerer, H., Pferschy, U. & Pisinger, D. Knapsack Problems (Springer, 2004).

  • 53.

    Schrijver, A. Theory of Linear and Integer Programming (John Wiley & Sons, 1998).

  • 54.

    Mukaka, M. M. Statistics corner: a guide to appropriate use of correlation coefficient in medical research. Malawi Med. J. 24, 69–71 (2012).

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Related Posts

    How Machine Learning has impacted Consumer Behaviour and Analysis
    Consumer Research

    How Machine Learning has impacted Consumer Behaviour and Analysis

    January 4, 2024
    Market Research The Ultimate Weapon for Business Success
    Consumer Research

    Market Research: The Ultimate Weapon for Business Success

    June 22, 2023
    Unveiling the Hidden Power of Market Research A Game Changer
    Consumer Research

    Unveiling the Hidden Power of Market Research: A Game Changer

    June 2, 2023
    7 Secrets of Market Research Gurus That Will Blow Your Mind
    Consumer Research

    7 Secrets of Market Research Gurus That Will Blow Your Mind

    May 8, 2023
    The Shocking Truth About Market Research Revealed!
    Consumer Research

    The Shocking Truth About Market Research: Revealed!

    April 25, 2023
    market research, primary research, secondary research, market research trends, market research news,
    Consumer Research

    Quantitative vs. Qualitative Research. How to choose the Right Research Method for Your Business Needs

    March 14, 2023
    Next Post
    Cold Chain Tracking and Monitoring Market: Research Report Covers Updated Data on Key Players Considering Impact of COVID 19

    Building Film Materials Market: Research Report Covers Updated Data on Key Players Considering Impact of COVID 19

    Categories

    • Consumer Research
    • Data Analysis
    • Data Collection
    • Industry Research
    • Latest News
    • Market Insights
    • Marketing Research
    • Survey Research
    • Uncategorized

    Recent Posts

    • Ipsos Revolutionizes the Global Market Research Landscape
    • How Machine Learning has impacted Consumer Behaviour and Analysis
    • Market Research: The Ultimate Weapon for Business Success
    • Privacy Policy
    • Terms of Use
    • Antispam
    • DMCA

    Copyright © 2024 Globalresearchsyndicate.com

    Welcome Back!

    Login to your account below

    Forgotten Password?

    Retrieve your password

    Please enter your username or email address to reset your password.

    Log In
    This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Cookie settingsACCEPT
    Privacy & Cookies Policy

    Privacy Overview

    This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience.
    Necessary
    Always Enabled
    Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
    Non-necessary
    Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.
    SAVE & ACCEPT
    No Result
    View All Result
    • Latest News
    • Consumer Research
    • Survey Research
    • Marketing Research
    • Industry Research
    • Data Collection
    • More
      • Data Analysis
      • Market Insights

    Copyright © 2024 Globalresearchsyndicate.com