New York City-based Mount Sinai Health System has received an HHS grant to build a second “big omics data engine,” named BODE 2, to advance translational bioinformatics research and data-enabled clinical care.
BODE 2 will replace Mount Sinai’s original BODE supercomputer at the end of this year. The new data engine, funded by the $2 million grant, will operate at a speed nearly double that of BODE and will give researchers secure access to even more diverse data sources, allowing for a bidirectional flow of information between researchers and point-of-care programs.
Initial projects facilitated by BODE 2 will include machine learning-powered analysis of whole-genome-sequencing datasets to advance new and existing treatments for Alzheimer’s disease, and a high-powered analysis of genomic, molecular, behavioral, imaging, environmental and clinical data to explore the biological causes of heart, blood, lung and sleep disorders.
“Based on our experiences with BODE, BODE 2 is designed to provide our researchers and clinicians, and their external partners in Mount Sinai-led national research projects, with the necessary infrastructure to achieve faster results for greater scientific throughput, increased fidelity in their simulations and analysis, and seamless migration of research applications to the software environment for enhanced scientific productivity,” Patricia Kovatch, senior associate dean for scientific computing and data science at Mount Sinai’s Icahn School of Medicine, said in a news release.
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